I am the Frederick H. Rawson Distinguished Service Professor of Medicine and Computer Science and the Jim and Karen Frank Director of the Center for Translational Data Science (CTDS) at the University of Chicago.

I have been a Partner of Analytic Strategy Partners LLC since 2017.

From 2002 to 2016, I was the founder and Managing Partner of Open Data Group. Open Data Group provided services and products so that companies can build and deploy machine learning and AI models. Open Data is now ModelOp. From 2011 to 2018, I was the co-founder and chief scientist at HealthSeq Asia, a biotech startup, which was acquired in 2018. From 1996 to 2001, I was the Founder and CEO of Magnify, which is now part of LexisNexis Risk Solutions and provides predictive analytics solutions to the insurance industry.

I am the Chair of the not-for-profit Open Commons Consortium, which develops and operates clouds to support research in science,
medicine, health care, and the environment.

From 2011-2024, I was the Chief Research Informatics Officer (CRIO) of the Biological Sciences Division at the University of Chicago.

I can be reached via Linkedin.

Honors and Awards

  • Sigma Xi Fellow, 2025

  • ACM Fellow, 2016

  • AAAS Fellow, 2013

  • Federal 100 Award Winner, 2013

  • Pritzker Scholar, University of Chicago, 2011

Advisory Boards

  • From 2024 - 2025, I was the Co-Chair of the Defense Science Board (DSB) Task Force on Balancing Security, Reliability, and Technological Advantage in Generative Artificial Intelligence for Defense.

  • From 2017 - 2024, I was a member of the Science Advisory Board (SAB) for the National Oceanic and Atmospheric Administration (NOAA).

  • From 2022 - 2024, I was the Co-Chair of the Defense Science Board (DSB) Task Force on Digital Engineering Capability to Automate Testing and Evaluation.

  • From 2014 - 2021, I was a member of the National Cancer Institute's Frederick National Laboratory Advisory Committee (FNLAC).

  • From 2013 - 2016, I was a committee Member of the National Research Council (NRC) study: Future Directions for NSF Advanced Computing Infrastructure, 2017-2020.

  • From 2013 to 2014, I was a Committee Member of the National Research Council (NRC) study: A Review of U.S. Navy Cyber Defense Capabilities.

  • From 2011 to 2013, I was the Co-Chair of the Defense Science Board Task Force on Cyber Security and Reliability in a Digital Cloud.

  • From 2009 to 2014, I was a member of the NASA Advisory Council (NAC)'s Information Technology Infrastructure Committee.

  • From 2008 to the present, I have been the Director of the Open Cloud Consortium (OCC).

  • From 2005 - 2013, I was a Member of the Board of Directors of the ACM Special Interest Group on Knowledge Discovery and Data Mining (SIGKDD).

  • From 1998 to 2010, I was the Director of the Data Mining Group, which develops the Predictive Model Markup Language.

  • From its founding in 1999 until 2003, I was a Member of Board of Directors of Infoblox (NYSE: BLOX).